The Motor Endplate
نویسندگان
چکیده
منابع مشابه
The Fine Structure of Motor Endplate Morphogenesis
The fine structure of the developing neuromuscular junction of rat intercostal muscle has been studied from 16 days in utero to 10 days postpartum. At 16 days, neuromuscular relations consist of close membrane apposition between clusters of axons and groups of myotubes. Focal electron-opaque membrane specializations more intimately connect axon and myotube membranes to each other. What relation...
متن کاملReinnervation of motor endplate-containing and motor endplate-less muscle grafts.
Damaged muscle fibers degenerate and are phagocytosed, but their connective tissue sheaths and myogenic cells survive. New myofibers regenerate within the connective tissue sheath and functional reinnervation is restored. The present study compared regenerating myofibers and their reinnervation in muscle grafts where the original motor endplates were removed and when they were present. In regen...
متن کاملMotor endplate cholinesterase in human skeletal muscle.
The activity and properties of cholinesterase (ChE) of the motor endplate and its fractions were studied in isolated human skeletal muscle. This preparation was used since the ChE activity of the membrane preparation was localized only in the motor endplate. The endplate ChE was stable in the isolated membrane for 4 weeks at 4 degrees C. The specific activity of the extracted ChE of human muscl...
متن کاملA Linear Dose-Response Curve at the Motor Endplate
The motor endplate of frog sartorius muscle was voltage clamped and the peak current to different concentrations of acetylcholine and carbachol applied in the perfusing fluid was measured. Perfusing fluid was hypertonic in order to suppress contractions. Current responses were smooth and reached a peak value within 2-5 s. The dose-response curve was usually linear even with concentrations of 10...
متن کاملMotor endplate remodeling in some cases with congenital myasthenic syndrome.
The architecture of motor endplates in three cases with congenital myasthenic syndrome (CMS) was compared with ultrastructure of the normal control neuromuscular junction (NMJ). The remodeling of postsynaptic region was observed in all three individuals. The most conspicuous abnormalities seen in the slow channel syndrome was the vacuolization and disorganization of secondary synaptic clefts wh...
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ژورنال
عنوان ژورنال: Journal of Neuropathology and Experimental Neurology
سال: 1965
ISSN: 0022-3069
DOI: 10.1097/00005072-196510000-00013